Hope for Empty Nose Syndrome: Unveiling the Potential of Stem Cell Therapy

Empty Nose Syndrome (ENS) stands as a rare, yet distressing, consequence of nasal turbinate resection surgery. Those who undergo procedures aimed at alleviating breathing difficulties often find themselves grappling with paradoxical nasal obstruction, dryness, crusting, and an overwhelming sense of breathing difficulty. In this intricate landscape of post-surgical complications, the journey through Empty Nose Syndrome leads us to explore the promising realm of stem cell therapy, a beacon of hope for those seeking relief

Understanding the Pathology:

The root cause of ENS lies in the resection of nasal turbinates, specifically the inferior turbinate, a crucial component in warming and filtering the air we breathe. Initially, the removal may seem beneficial, allowing for increased air passage and improved respiration. However, the collateral damage emerges in the form of neuropathic injury to the nerves within these structures.
The neuropathic injury primarily affects the long sphenopalatine nerve and the anterior branches of the maxillary nerve, both integral parts of the Trigeminal nerve. This nerve damage mirrors the concept of “phantom limb pain,” where severed nerve endings continue to send incorrect signals to the brain, creating the perception of a blocked nose. Attempts to reconstruct nasal architecture through implants or grafts have proven futile, highlighting the core issue: nerve damage.

Stem Cells: The Beacon of Healing:

To tackle the neuropathic injury at the heart of Empty Nose Syndrome, the use of stem cells emerges as a potential solution. Stem cells are neurotrophic, meaning they foster the growth and repair of nerve cells. In essence, stem cells present a regenerative pathway to mitigate neuropathic damage. Drawing parallels with the success of stem cells in treating conditions like phantom limb pain and refractive surgery complications, the focus on repairing severed and damaged neurons becomes pivotal.

Treatment Approach:

Addressing ENS through stem cell therapy involves strategic injections close to the branches of the maxillary division of the Trigeminal nerve and the long sphenopalatine nerve. Surgeons at EuroStemCell.life, specializing in craniomaxillofacial surgery, possess the expertise to navigate these intricate areas. Their unique proficiency sets them apart, ensuring precise administration of stem cell injections in the specific regions affected.

Combining Forces: Hyperbaric Oxygen Therapy (HBOT) and Stem Cells:

The synergy between hyperbaric oxygen therapy (HBOT) and stem cell therapy enhances the potential for positive outcomes. Stem cells thrive in oxygen-rich environments, and HBOT provides the ideal setting for these cells to differentiate effectively into neurons. This combined approach harnesses the healing power of stem cells while optimizing their functionality through enhanced oxygen availability.

The Role of Stem Cells in Nerve Repair:

Stem cells, known for their neurotrophic properties, have the potential to encourage nerve growth and repair. In the context of Empty Nose Syndrome, stem cell therapy aims to mitigate neuropathic injury by fostering the regeneration of damaged nerve cells. The crux of this approach lies in injecting stem cells near the branches of the maxillary division of the Trigeminal nerve and the long sphenopalatine nerve. This targeted administration is crucial, and EuroStemCell.life stands out for having craniomaxillofacial surgeons trained in precisely identifying and accessing these specialized areas.

The EuroStemCell.life Advantage:

What sets EuroStemCell.life apart is not just its commitment to stem cell therapy but the integration of craniomaxillofacial surgeons into its team. This unique blend of surgical expertise ensures precise and targeted administration of stem cell injections, a critical factor often overlooked by other commercial stem cell laboratories.

Hope on the Horizon:

While there are no foolproof surgical cures for Empty Nose Syndrome, the integration of stem cell therapy and HBOT offers a relatively low-risk avenue for potential relief. Early intervention proves pivotal, emphasizing the importance of initiating stem cell treatment and HBOT at the earliest signs of ENS. It is worth noting that multiple treatments may be necessary, and the results can vary.


Empty Nose Syndrome is a formidable adversary, affecting individuals who sought relief through nasal surgery. The integration of stem cell therapy and hyperbaric oxygen therapy introduces a ray of hope into the lives of those grappling with the debilitating effects of ENS. Professor Vickers and his team at EuroStemCell.life exemplify a commitment to pioneering solutions, offering not just treatment but a comprehensive understanding of the intricate web of nerves impacted by ENS. As we stand at the intersection of medical innovation and patient care, the promise of a better quality of life for ENS sufferers beckons, guided by the regenerative potential of stem cells.

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